Neural tube closure is a key early event in brain and spinal cord development in which the planar epithelium of the neural plate folds at the midline along the anteroposterior axis and the lateral edges of the neural plate move dorsally contact each other and fuse dorsally to form the neural tube fig.
Floor plate neural tube.
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The floor plate located in the ventral most region of the neural tube has a lot of unique characteristics including a low cell proliferation rate.
The mechanisms by which this region specific proliferation rate is regulated remain elusive.
Primary neurulation and secondary neurulation.
Primary neurulation begins after the neural plate.
Development of the neural tube from mesenchyme caudal to the posterior neuropore tail bud.
The floor plate is a specialized glial structure with secretory function that spans the rostral caudal axis from the midbrain to the tail regions.
29 5 dorsal fusion first occurs in the region of the cervical spinal cord primordium.
The neural tube is composed of a number of neural progenitors and postmitotic neurons distributed in a quantitatively and spatially precise manner.
The floor plate located in the ventral most region of the neural tube has a lot of unique characteristics including a low cell proliferation rate.
T he floor plate is a transient embryonic organizing center located at the ventral midline of the neural tube that profoundly influences the development of the vertebrate central nervous system.
The neural tube is composed of a number of neural progenitors and postmitotic neurons distributed in a quantitatively and spatially precise manner.
Analogous to floor plate but on the dorsal surface of the neural tube.
The floor plate is a structure integral to the developing nervous system of vertebrate organisms.
The specialized histological features of floor plate cells have long been recognized 1 1 but only comparatively recently have the remarkable patterning activities of this ventral midline neural.
The neural tube develops in two ways.
The mechanisms by which this region specific proliferation rate is regulated remain elusive.
The floor plate is one of first structures that differentiate in the developing nervous system.
The neural crest cells which develop in the region between the neural tube and epidermis but then migrate to new locations.
Development of the neural tube from neural plate.
Primary neurulation divides the ectoderm into three cell types.
The externally located epidermis.
The internally located neural tube.
A dual origin for spinal cord floor plate is indicated by zebra fish mutant analyses and quail chick chimera experiments which show that the medial floor plate is derived from the node expresses shh and helps induce lateral floor plate in adjoining neural tube.
